STEVEN B. HEYMSFIELD, M.D.; JANET L. SMITH-ANDREWS, M.M.SC., R.D.; THEODORE HERSH, M.D.
Two patients with malabsorption syndrome and weight loss refractory to conventional pharmacologic and dietary therapy were evaluated on a metabolic ward. Baseline studies indicated moderate to severe protein-energy malnutrition, and severe energy, fat, and nitrogen malabsorption. Metabolic balance studies on low-fat elemental formulas infused nasoenterally over 18-hour periods indicated improved retention of nitrogen, phosphorus, calcium, magnesium, and energy when compared with a solid food diet. Because this dietary modification appeared to correct their malabsorption, both patients learned to insert the nasoenteral tube themselves, and a low-calorie solid-food diet combined with nocturnal tube feedings was continued at home. During the next 9 to 12 months, both patients had increases in body weight, and in the mass of fat-free tissue, skeletal muscle, and fat. This therapeutic approach may correct life-threatening semistarvation in selected patients.
HEYMSFIELD SB, SMITH-ANDREWS JL, HERSH T. Home Nasoenteric Feeding for Malabsorption and Weight Loss Refractory to Conventional Therapy. Ann Intern Med. ;98:168–170. doi: 10.7326/0003-4819-98-2-168
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Published: Ann Intern Med. 1983;98(2):168-170.
Celiac Disease and Malabsorption, Gastroenterology/Hepatology.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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