SANJEEV PRAKASH, M.D.; NARINDER K MEHRA, PH.D.; ANAND N MALAVIYA, M.D.
To the editor: The frequency of the HLA-B27 antigen in samples of the normal Indian population and its association with ankylosing spondylitis, Reiter's disease, and other spondyloarthropathies is similar to those reported in Western studies. The HLA-B27 antigen has been detected by us in 5.9% of 118 controls, 94% of 51 patients with ankylosing spondylitis (relative risk, 254), 83% of 36 patients with Reiter's disease (relative risk, 79), and 84% of 25 patients with "unclassifiable" seronegative peripheral arthritis (relative risk, 83) (1). This last group of patients are primarily males with seronegative asymmetric arthritis mainly involving large joints of lower
PRAKASH S, MEHRA NK, MALAVIYA AN. HLA-B27 Homozygosity in Seronegative Spondyloarthropathies. Ann Intern Med. ;98:676. doi: 10.7326/0003-4819-98-5-676
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Published: Ann Intern Med. 1983;98(5_Part_1):676.
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