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The safe and effective use of cancer chemotherapy requires a thorough knowledge of the chemistry and pharmacology of these drugs as well as the cellular biochemistry that controls their activity. Most textbooks of pharmacology and medical oncology have not adequately covered these areas, which are essential to the rational timing of cancer chemotherapy and optimal combination of these agents. Dr. Chabner and his colleagues have filled this need with a concise, well-written, and well-edited book.
The first section presents principles of cancer treatment, pharmacokinetics, cell kinetics, drug monitoring, and late complications. The chapters by Goldman on pharmacokinetics at the cellular
Pharmacologic Principles of Cancer Treatment.. Ann Intern Med. 1983;98:694. doi: 10.7326/0003-4819-98-5-694_1
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Published: Ann Intern Med. 1983;98(5_Part_1):694.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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