Skip Navigation
Menu
Brief Reports |1 June 1983

Serum Antibodies Against Mouse Mammary Tumor-Virus-Associated Antigen Detected Nine Months Before Appearance of a Breast Carcinoma

MAN-CHlU POON, M. D.; MILAN TOMANA, Ph.D; WILLIAM NIEDERMEIER, Ph.D.

Article, Author, and Disclosure Information
Author, Article, and Disclosure Information
▸Requests for reprints should be addressed to Man-Chiu Poon, M.D.; Division of Hematology/Oncology, Department of Medicine, University of Alabama in Birmingham, University Station; Birmingham, AL 3S294.
  • University of Alabama
    , and the
    Birmingham Veterans Administration Medical Center
    ;
    Birmingham, Alabama
×
FULL TEXT

Abstract

Earlier investigations (1-4) showed an immunologic relation between human breast cancer and mouse mammary tumor virus (MMTV). The presence of antibodies in sera of patients with breast cancer reacting with antigens in the cytoplasm of mouse mammary tumor cells was shown by various methods including indirect immunofluorescence (5). This reactivity could be abolished by absorption of the sera with MMTV (5, 6) or intracytoplasmic type A particles (7). The specificity of the reactivity of human antibodies with MMTV-associated antigens has been questioned by some investigators (8). Our patient's serum, initially nonreactive with MMTV-associated antigens, became reactive 9 months before the

FULL TEXT
PDF
Not Available
Citations
Citation

POON M, TOMANA M, NIEDERMEIER W. Serum Antibodies Against Mouse Mammary Tumor-Virus-Associated Antigen Detected Nine Months Before Appearance of a Breast Carcinoma. Ann Intern Med. ;98:937–938. doi: 10.7326/0003-4819-98-6-937

Download citation file:

© 2018

×
Permissions

Published: Ann Intern Med. 1983;98(6):937-938.

DOI: 10.7326/0003-4819-98-6-937

12 Citations

Related Articles
Antibody to Human T-Cell Leukemia Virus Membrane Antigens, Beta2-Microglobulin Levels, and Thymosin Alpha1 Levels in Hemophiliacs and Their Spouses
Annals of Internal Medicine; 100 (2): 178-182
Are All Diseases Infectious?
Annals of Internal Medicine; 125 (10): 844-851
Disappearance of Humoral Thyroid Autoimmunity after Complete Removal of Thyroid Antigens
Annals of Internal Medicine; 139 (5_Part_1): 346-351
High Prevalence of Antibodies to Intestinal Epithelial Antigens in Patients with Inflammatory Bowel Disease and Their Relatives
Annals of Internal Medicine; 110 (10): 786-794
View MoreView Less

Related Topics
Breast Cancer
Hematology/Oncology
Infectious Disease

Breast Cancer, Hematology/Oncology, Infectious Disease.

PubMed Articles
Translating the anti-myeloma activity of Natural Killer cells into clinical application.
Cancer Treat Rev 2018;
γ-glutamylcysteine exhibits anti-inflammatory effects by increasing cellular glutathione level.
Redox Biol 2018;
View More

Results provided by: PubMed

CONTINUE WITH LIMITED ACCESS
Annals of Internal Medicine
To receive access to the full text of freely available articles, alerts, and more. You will be directed to acponline.org to complete your registration.
×
acp link acp
silverchair link silverchair

Copyright © 2018 American College of Physicians. All Rights Reserved.

Print ISSN: 0003-4819 | Online ISSN: 1539-3704

Privacy Policy

|

Conditions of Use

This site uses cookies. By continuing to use our website, you are agreeing to our privacy policy. | Accept
×

You need a subscription to this content to use this feature.

×
PDF Downloads Require Access to the Full Article.
Annals of Internal Medicine
To receive access to the full text of freely available articles, alerts, and more. You will be directed to acponline.org to complete your registration.
×
Access to this Free Content Requires Users to be Registered and Logged In. Please Choose One of the Following Options
Annals of Internal Medicine
To receive access to the full text of freely available articles, alerts, and more. You will be directed to acponline.org to complete your registration.
×