ROBERT E. FONTAINE, M.D.; ERNESTO RUIZ-TIBEN, PH.D.
To the editor: Dr. Cook has presented a valuable update of recent and important changes affecting the chemotherapy of schistosomiasis (1). We agree that the low toxicity of available compounds allows treatment of even the lightest infections. But given the difficulty in showing eggs in some schistosomal disease states, we do not think it necessary to have evidence of eggs before initiating chemotherapy.
All schistosome species commonly affecting humans can produce severe morbidity from ectopic infections involving the central nervous system. Given a compatible clinical and laboratory profile, the diagnosis of ectopic central nervous system schistosomiasis can be reached by
FONTAINE RE, RUIZ-TIBEN E. Schistosomal Egg Viability and Treatment Decisions. Ann Intern Med. ;98:1031. doi: 10.7326/0003-4819-98-6-1031_1
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Published: Ann Intern Med. 1983;98(6):1031.
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