HAROLD W. JAFFE, M.D.; KEEWHAN CHOI, Ph.D.; PAULINE A. THOMAS, M.D.; HARRY W. HAVERKOS, M.D.; DAVID M. AUERBACH, M.D.; MARY E. GUINAN, Ph.D., M.D.; MARTHA F. ROGERS, M.D.; THOMAS J. SPIRA, M.D.; WILLIAM W. DARROW, Ph.D.; MARK A. KRAMER, Ph.D.; STEPHEN M. FRIEDMAN, M.D.; JAMES M. MONROE, M.S.; ALVIN E. FRIEDMAN-KIEN, M.D.; LINDA J. LAUBENSTEIN, M.D.; MICHAEL MARMOR, Ph.D.; BIJAN SAFAI, M.D.; SELMA K. DRITZ, M.D.; SALVATORE J. CRISPI, B.A.; SHIRLEY L. FANNIN, M.D.; JOHN P. ORKWIS, B.S.; ALEXANDER KELTER, M.D.; WILMON R. RUSHING, M.P.H.; STEPHEN B. THACKER, M.D.; JAMES W. CURRAN, M.D., M.P.H.
To identify risk factors for the occurrence of Kaposi's sarcoma and Pneumocystis carinii pneumonia in homosexual men, we conducted a case-control study in New York City, San Francisco, Los Angeles, and Atlanta. Fifty patients (cases) (39 with Kaposi's sarcoma, 8 with pneumocystis pneumonia, and 3 with both) and 120 matched homosexual male controls (from sexually transmitted disease clinics and private medical practices) participated in the study. The variable most strongly associated with illness was a larger number of male sex partners per year (median, 61 for patients; 27 and 25 for clinic and private practice controls, respectively). Compared with controls, cases were also more likely to have been exposed to feces during sex, have had syphilis and non-B hepatitis, have been treated for enteric parasites, and have used various illicit substances. Certain aspects of a lifestyle shared by a subgroup of the male homosexual population are associated with an increased risk of Kaposi's sarcoma and pneumocystis pneumonia.
JAFFE HW, CHOI K, THOMAS PA, HAVERKOS HW, AUERBACH DM, GUINAN ME, et al. National Case-Control Study of Kaposi's Sarcoma and Pneumocystis carinii Pneumonia in Homosexual Men: Part 1, Epidemiologic Results. Ann Intern Med. 1983;99:145–151. doi: 10.7326/0003-4819-99-2-145
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Published: Ann Intern Med. 1983;99(2):145-151.
Hematology/Oncology, Infectious Disease.
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