KENNETH L. KOCH, M.D.; T. VINCENT SHANKEY, Ph.D.; GERALD S. WEINSTEIN, M.D.; ROBERT E. DYE, M.D.; ARTHUR B. ABT, M.D.; WILLIAM L. CURRENT, Ph.D.; M. ELAINE EYSTER, M.D.
A 36-year-old man had chronic, debilitating diarrhea due to cryptosporidiosis. This patient had longstanding common variable hypogammaglobulinemia and recurrent bacterial infections. Immunologic evaluation after discovery of Cryptosporidium showed lymphopenia with persistently reduced numbers of helper/inducer cells (OKT-4), variable numbers of suppressor/cytotoxic cells (OKT-8), OKT-4/OKT-8 ratio of 0.09, and increased levels of serum alpha-interferon, all of which describe the acquired immunodeficiency syndrome. Oocysts of Cryptosporidium were found in feces from the patient's cat, thus identifying a possible source of his infection. The patient had disseminated candidiasis, cytomegalovirus pneumonia, and cryptosporidiosis when he died.
KENNETH L. KOCH, T. VINCENT SHANKEY, GERALD S. WEINSTEIN, ROBERT E. DYE, ARTHUR B. ABT, WILLIAM L. CURRENT, et al. Cryptosporidiosis in a Patient with Hemophilia, Common Variable Hypogammaglobulinemia, and the Acquired Immunodeficiency Syndrome. Ann Intern Med. 1983;99:337–340. doi: 10.7326/0003-4819-99-3-337
Download citation file:
Published: Ann Intern Med. 1983;99(3):337-340.
Results provided by:
Copyright © 2017 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use