PETER G. STEINHERZ, M.D.; RUSSELL WALKER, M.D.; GEORGE KROLL, M.D.; PHILIP EXELBY, M.D.; LAUREL J. STEINHERZ, M.D.; MARY WEISER, R.N.; DENIS MILLER, M.D.
Patients with Hodgkin's disease may have neurologic symptoms without tumor involvement, or the disease may extend into the nervous system. Intracerebral disease is uncommon (1, 2). Meningeal disease occurs rarely as a terminal complication of long-standing disease. Eleven cases have been reported (3-10). Meningeal disease before diagnosis of systemic disease has been reported once (11). We report the case of a patient who presented with progressive weakness, paresthesias, pain, papilledema, and polyradiculopathy. Myelographic examination showed several root involvements with no epidural disease.
A 16-year-old man had a 9-kg weight loss. Findings in the physical examination were normal. Fatigue and progressive
STEINHERZ PG, WALKER R, KROLL G, EXELBY P, STEINHERZ LJ, WEISER M, et al. Lymphomatous Leptomeningitis as a Presenting Syndrome of Hodgkin's Disease. Ann Intern Med. ;99:342–343. doi: 10.7326/0003-4819-99-3-342
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Published: Ann Intern Med. 1983;99(3):342-343.
Hematology/Oncology, Leukemia/Lymphoma, Neurology.
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