FRIEDRICH CONRAD, M.D.; HOLGER BAUMGARTNER, M.D.; CHRISTIAN WIEDERMANN, M.D.; GEORG KLEIN, M.D.
To the editor: Because emotional sweating is under sympathetic control (1), clonidine, known to inhibit sympathetic tone (2), could be useful in the treatment of excessive emotional sweating (hyperhidrosis), a disorder that is still a therapeutic problem (1). Several reports imply a possible inhibition of sweating by clonidine in various conditions, including diabetic gustatory sweating (3, 4). In the summer of 1979, we tested clonidine in six hyperhidrotic patients (three palmar, two plantar, and one axillar) who had considered surgical sympathectomy. Informed consent was obtained before the study.
Intravenous clonidine, 1.8 mg/kg body weight, was tested twice (single blind) in
FRIEDRICH CONRAD, HOLGER BAUMGARTNER, CHRISTIAN WIEDERMANN, GEORG KLEIN. Clonidine and Hyperhidrosis. Ann Intern Med. 1983;99:570. doi: 10.7326/0003-4819-99-4-570_1
Download citation file:
Published: Ann Intern Med. 1983;99(4):570.
Copyright © 2017 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use