WALTER E. STAMM, M.D.; LAURA A. KOUTSKY, M.S.P.H.; JACQUELINE K. BENEDETTI, Ph.D; JOHN L. JOURDEN, B.A.; ROBERT C. BRUNHAM, M.D.; KING K. HOLMES, M.D., Ph.D
Twelve percent of 596 men presenting to a sexually transmitted disease clinic had positive urethral cultures for Chlamydia trachomatis, and 53% had microimmunofluorescent antibody to chlamydia. Prevalence of C. trachomatis urethral infection was greater in heterosexual than homosexual men (14% versus 5%; p < 0.01), in men under 20 years of age, and in blacks. Only 10% of men with gonococcal urethral infection lacked symptoms or signs of urethritis, whereas nearly 25% of men with C. trachomatis urethral infection had no signs and symptoms, 33% lacked abnormal numbers of leukocytes on urethral Gram stain, and 50% were identified and treated solely on the basis of a screening culture. The number of newly diagnosed cases found by screening cultures was 1.3 per 100 cultures for gonorrhea but 5.5 per 100 for chlamydial infection. Clinicians appropriately treated 91% of men with gonococcal urethritis on their initial visit before culture results were available versus only 51% of men with chlamydial urethral infection. Asymptomatic urethral infections in men eventually contribute to chlamydial infections in women, and culture screening for their detection appears warranted in high-risk populations.
STAMM WE, KOUTSKY LA, BENEDETTI JK, JOURDEN JL, BRUNHAM RC, HOLMES KK. Chlamydia trachomatis Urethral Infections in Men: Prevalence, Risk Factors, and Clinical Manifestations. Ann Intern Med. ;100:47–51. doi: 10.7326/0003-4819-100-1-47
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Published: Ann Intern Med. 1984;100(1):47-51.
Infectious Disease, Sexually Transmitted Infections.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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