ADAM LERNER, M.D.; JOHN M. DWYER, M.D., PH.D.
To the editor: Allergic reactions to vancomycin are not rare and can be serious when a patient is infected by an organism (usually staphylococci) for which there is no satisfactory alternate antibiotic agent (1, 2). We report the case of a woman infected with a methicillin-resistant Staphylococcus aureus who was twice successfully hyposensitized to vancomycin after she had a severe systemic allergic reaction to the drug.
Our 36-year-old patient had a history of recurrent staphylococcal skin abscesses since childhood. She presented with a chronic, subcutaneous infection of her right elbow and a breast abscess. Both wounds contained methicillin-resistant S. aureus
LERNER A, DWYER JM. Desensitization to Vancomycin. Ann Intern Med. ;100:157. doi: 10.7326/0003-4819-100-1-157_1
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Published: Ann Intern Med. 1984;100(1):157.
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