ROBERT A. GOLDSTEIN, M.D., PH.D.; ROY PATTERSON, M.D.
It has been estimated that medical inpatients receive a total of 90 million courses of drug therapy per year and the frequency of adverse drug reactions is about 5% (1). By limiting the use of the term allergic to those reactions that are immunologically mediated or can reasonably be presumed to be, estimates are that drug allergy may account for 6% to 10% of these adverse reactions (2).
Recognizing the magnitude of this problem, The National Institute of Allergy and Infectious Diseases noted that, if the knowledge gained from research findings in drug allergy could be widely used, it should
GOLDSTEIN RA, PATTERSON R. Drug Allergy: Prevention, Diagnosis, and Treatment. Ann Intern Med. ;100:302–303. doi: 10.7326/0003-4819-100-2-302
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Published: Ann Intern Med. 1984;100(2):302-303.
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