BRUCE L. EVATT, M.D.; ROSEMARY B. RAMSEY, M.S.; DALE N. LAWRENCE, M.D.; LAWRENCE D. ZYLA, M.P.H.; JAMES W. CURRAN, M.D.
Since mid-1981 the Centers for Disease Control (CDC) has received reports of more than 1900 cases of the acquired immunodeficiency syndrome. These patients had either Kaposi's sarcoma confirmed by biopsy or a life-threatening opportunistic infection confirmed by biopsy or culture. In January 1982 a case of a hemophiliac with Pneumocystis carinii pneumonia was reported to the CDC, and by July 1982 two other hemophiliacs had developed P. carinii pneumonia. During the next 12 months a total of 22 confirmed cases of the acquired immunodeficiency syndrome occurred in hemophiliacs, 17 in the United States and 5 outside the United States. We report the nature of the epidemic of the acquired immunodeficiency syndrome in hemophiliacs and summarize pertinent clinical aspects.
EVATT BL, RAMSEY RB, LAWRENCE DN, ZYLA LD, CURRAN JW. The Acquired Immunodeficiency Syndrome in Patients with Hemophilia. Ann Intern Med. 1984;100:499–504. doi: 10.7326/0003-4819-100-4-499
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Published: Ann Intern Med. 1984;100(4):499-504.
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