CHARLES G. MOERTEL, M.D.; PAUL F. ENGSTROM, M.D.; ALLAN J. SCHUTT, M.D.
Managing patients with the carcinoid tumor, whose condition is sometimes complicated by the carcinoid syndrome, presents a difficult challenge. Surgical treatment is usually curative in early stages and even in advanced stages may provide palliation. Nonsurgical treatment, however, has been disappointing. Radiation therapy is only rarely helpful, and cytotoxic drugs have produced less than optimal results.
Recent interest in the possible effectiveness of hormonal alteration has been raised by reports of the presence of estrogen receptors in carcinoid tumor (1) and of a patient who had symptomatic improvement of the carcinoid syndrome with tamoxifen therapy (2). Particularly impressive has been
CHARLES G. MOERTEL, PAUL F. ENGSTROM, ALLAN J. SCHUTT. Tamoxifen Therapy for Metastatic Carcinoid Tumor: A Negative Study. Ann Intern Med. 1984;100:531–532. doi: 10.7326/0003-4819-100-4-531
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Published: Ann Intern Med. 1984;100(4):531-532.
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