MICHAEL FRIEDLAND, M.D.; ASHOK BAJRACHARYA, M.D.; ZALMEN ARLIN, M.D.
To the editor: A recent article by Roach (1) described a partial response to isotretinoin in a patient with metastatic malignant eccrine poroma. We recently treated a patient with this disease with the regimen described by Roach, but without response.
A 53-year-old woman developed a posterior chest wall mass in 1980 and after initial local treatment remained asymptomatic. In February 1982 she received radiation therapy for a local skin recurrence. In September 1982 she developed a further recurrence in the skin of the left breast and left posterior chest wall and was treated with additional radiation therapy and topical fluorouracil.
FRIEDLAND M, BAJRACHARYA A, ARLIN Z. Malignant Eccrine Poroma and Isotretinoin. Ann Intern Med. ;100:614. doi: 10.7326/0003-4819-100-4-614
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Published: Ann Intern Med. 1984;100(4):614.
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