ALAN I. LEIBOWITZ, M.D.; ADRIAN O. VLADUTIU, M.D., PH.D.
To the editor: Recently, Foutch and associates (1) reported the presence of hepatitis B surface antigen (HBsAg) and its antibody (anti-HBs) in 13 patients. The authors thought that this finding showed that certain persons developed two discrete infections with hepatitis B virus (HBV). Indeed, previous findings of the simultaneous presence of HBsAg and anti-HBs were explained by infections with two subtypes of HBV (2). The concomitant presence of HBsAg with true anti-HBs could be found, for a very short time, during the clearing of HBsAg after an acute infection.
It is difficult to believe that the patients can clear an
LEIBOWITZ AI, VLADUTIU AO. Concomitant Hepatitis B Surface Antigen and Antibody. Ann Intern Med. ;100:615. doi: 10.7326/0003-4819-100-4-615_2
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Published: Ann Intern Med. 1984;100(4):615.
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