JOSEPH J. FALLON, M.D.; PAUL J. GREEN, PH.D.
To the editor: The standardization of serum cortisol responses to low- and high-dose dexamethasone testing for Cushing's syndrome reported by Ashcraft and colleagues (1) is an economic and technical advance. We wish to report a false-positive study secondary to estrogen administration and also to show the nonspecificity of acid phosphatase values determined in the prostate by the substrate-specific enzymatic method.
An 81-year-old man with probable metastatic adenocarcinoma of the prostate was hospitalized for bone pain that was not relieved by diethylstilbestrol. The patient had a bone biopsy that showed adenocarcinoma of unknown primary site, and a computed tomographic scan showed
FALLON JJ, GREEN PJ. A False-Positive Response in Dexamethasone Testing. Ann Intern Med. ;100:770. doi: 10.7326/0003-4819-100-5-770_1
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Published: Ann Intern Med. 1984;100(5):770.
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