STEVEN SNYDER, M.D.
To the editor: I read with interest the letter from Dr. Parker (1) in the December issue. I write to describe the cases of two patients who developed aseptic necrosis of the hips while they were taking physiologic or slightly supraphysiologic doses of hydrocortisone.
A 36-year-old man had a craniotomy in 1974 for removal of a large chromophobe adenoma. Surgery was followed by radiation therapy. A preoperative thyroxine level was 3.4 ng/L, and the free thyroxine index was 90 (normal range, 150 to 350). Postoperatively, the patient was empirically placed on 60 mg/d of hydrocortisone in divided doses, as well
SNYDER S. Avascular Necrosis and Corticosteroids. Ann Intern Med. ;100:770. doi: 10.7326/0003-4819-100-5-770_3
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Published: Ann Intern Med. 1984;100(5):770.
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