HOWARD A. SCHNEIDER, M.D.; RICHARD A. YONKER, D.O.; SELDEN LONGLEY, M.D.; PAUL KATZ, M.D.; JOHN MATHIAS, M.D.; RICHARD S. PANUSH, M.D.
Esophageal dysfunction develops in approximately 90% of patients with progressive systemic sclerosis (scleroderma) or mixed connective tissue disease (1). Abnormal esophageal motility may be one of the earliest manifestations of scleroderma because of smooth muscle involvement (2, 3). Smooth muscle is found in the lower two thirds of the esophagus and in the lower esophageal sphincter. Manometric measurements confirm the incoordination and loss of effective contractions that often progress to complete absence of esophageal contractions and reduced lower esophageal sphincter tone (4). We reviewed esophageal manometric tracings from patients with or without rheumatic disease to determine whether low-amplitude aperistalsis or
HOWARD A. SCHNEIDER, RICHARD A. YONKER, SELDEN LONGLEY, PAUL KATZ, JOHN MATHIAS, RICHARD S. PANUSH. Scleroderma Esophagus: A Nonspecific Entity. Ann Intern Med. 1984;100:848–850. doi: 10.7326/0003-4819-100-6-848
Download citation file:
Published: Ann Intern Med. 1984;100(6):848-850.
Esophageal Disorders, Gastroenterology/Hepatology, Rheumatology, Scleroderma.
Results provided by:
Copyright © 2017 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use