FRANCIS W. CHANDLER, D.V.M., Ph.D.; ELIZABETH H. WHITE, M.S.; CAREY S. CALLAWAY, B.S.; THOMAS J. SPIRA, M.D.; EDWIN P. EWING Jr., M.D.
Although the cause of the acquired immunodeficiency syndrome is unknown, epidemiologic evidence shows that this syndrome is transmissible both sexually and parenterally (1). Recent serologic and virologic studies suggest a link between the syndrome and infection with a retrovirus related to the human T-cell leukemia virus (2-4).
After electron microscopic studies of lymph nodes from homosexual men with unexplained lymphadenopathy failed to show a virus-like agent (5), we systematically searched for virus-like particles in tissue samples from the intestine, salivary gland, testis, and prostate from patients who had died of the acquired immunodeficiency syndrome. These organs were studied because of
CHANDLER FW, WHITE EH, CALLAWAY CS, SPIRA TJ, EWING EP. Unidentified Virus-Like Particles in the Intestine of Patients with the Acquired Immunodeficiency Syndrome. Ann Intern Med. ;100:851–853. doi: 10.7326/0003-4819-100-6-851
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Published: Ann Intern Med. 1984;100(6):851-853.
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