JOHN T. DUNN, M.D.
We asked 54 thyroidologists how they would treat each of four patients having moderate hyperthyroidism of Graves' disease and a thyroid gland weighing 70 g (three to four times normal). For a 19-year-old woman, 67% of thyroidologists recommended an initial course of therapy with antithyroid drugs, usually for 1 year; 24% favored radioiodine treatments; and 9%, surgery. Choices for treating a 19-year-old man were similar. For a 29-year-old man, 44% of thyroidologists preferred drug therapy; 50%, radioiodine; and 6%, surgery. For a 29-year-old woman, choices were similar to those for the 29-year-old man, except for a slight preference for drugs over radioiodine. If hyperthyroidism recurred after a first course of antithyroid drugs, the consultants favored radioiodine treatments and surgery about equally, except in the 29-year-old man, in whom radioiodine was preferred. This survey shows considerable variation among experts in treating hyperthyroidism in young adults.
DUNN JT. Choice of Therapy in Young Adults with Hyperthyroidism of Graves' Disease: A Brief, Case-Directed Poll of Fifty-Four Thyroidologists. Ann Intern Med. ;100:891–893. doi: 10.7326/0003-4819-100-6-891
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Published: Ann Intern Med. 1984;100(6):891-893.
Endocrine and Metabolism, Thyroid Disorders.
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