AGUSTÍN CABANILLAS-ARIAS, M.D.; JUAN JOSÉ LAHUERTA-PALACIOS, M.D.; CRUZ ORTIZ-CONDE, M.D.; J. MONTERO-CASTILLO, M.D.
To the editor: We read with interest the article by Fauci and colleagues (1) on Wegener's granulomatosis. Despite references to neoplasias as probable consequences of the use of cyclophosphamide in the treatment of Wegener's granulomatosis, these two entities have yet to be reported in primary association. Recently, we studied a patient with polycythemia vera in the process of evolving toward frank leukemia associated with a systemic necrotizing granulomatous vasculitis with the clinical pattern of Wegener's granulomatosis.
A 79-year-old woman was diagnosed as having polycythemia vera in 1975, the evolution of which was controlled for 7 years by alkylating agents and
CABANILLAS-ARIAS A, LAHUERTA-PALACIOS JJ, ORTIZ-CONDE C, MONTERO-CASTILLO J. Evolving Polycythemia Vera and Wegener's Granulomatosis. Ann Intern Med. ;101:399. doi: 10.7326/0003-4819-101-3-399_2
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Published: Ann Intern Med. 1984;101(3):399.
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