BARBARA ROMANOWSKI, M.D.; JONATHAN WEBER, M.B.
To the editor: The recent emergence of the acquired immunodeficiency syndrome and attempts to identify simple screening tests have prompted suggestions for investigating asymptomatic patients at high risk. Possible screening tests include a full blood count with differential, to assess total lymphocyte numbers; estimation of T-lymphocyte subsets; qualitative assessment of lymphocyte function by proliferative studies; in-vivo testing of cutaneous delayed-type hypersensitivity; and various serum markers, particularly acid-labile interferon and beta-2 microglobulin. None of these tests are specific for the syndrome and many are expensive and time consuming.
Candidal infection is almost universal in patients with the syndrome and in many
ROMANOWSKI B, WEBER J. Oral Candidiasis and the Acquired Immunodeficiency Syndrome. Ann Intern Med. ;101:400–401. doi: 10.7326/0003-4819-101-3-400_2
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Published: Ann Intern Med. 1984;101(3):400-401.
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