SCOTT ANDERSON, M.D.; NANETTE K. WENGER, M.D.
To the editor: Ellrodt and colleagues (1) recently reported an association between severe neutropenia and the use of sustained-release procainamide. Seven of the eight patients described presented with fever and constitutional symptoms; only one patient was asymptomatic. Although we had not seen symptomatic severe neutropenia associated with the administration of sustained-release procainamide, we chose to determine the incidence of this potentially serious complication in ambulatory patients treated at a large urban hospital.
All patients who had prescriptions for sustained-release procainamide filled at the Grady Memorial Hospital outpatient pharmacy from September 1983 to February 1984 were identified by a computer search
ANDERSON S, WENGER NK. Sustained-Release Procainamide and Neutropenia. Ann Intern Med. ;101:404. doi: 10.7326/0003-4819-101-3-404_1
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Published: Ann Intern Med. 1984;101(3):404.
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