J. MARTIN MILLER, M.D.; JOEL I. HAMBURGER, M.D.; SUDHA R. KINI, M.D.
To the editor: Gharib and associates (1) report that 333 of 1970 patients with thyroid nodules who were treated at the Mayo Clinic had "suspicious" findings on fine-needle aspiration biopsy. They advised surgical excision of all such lesions because 24% of 253 excised lesions were malignant. Comparison with the published experience with fine-needle aspiration biopsy or large-needle aspiration biopsy on our first 2000 patients shows important differences (2). Gharib and associates placed their nodules in three diagnostic categories: malignant, 5%; suspicious, 17%; and benign, 78%. We also had three categories: probably malignant, 15%; possibly malignant, 17%; and probably benign, 67%.
MILLER JM, HAMBURGER JI, KINI SR. Thyroid Nodules and Needle Biopsy. Ann Intern Med. ;101:718. doi: 10.7326/0003-4819-101-5-718_1
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Published: Ann Intern Med. 1984;101(5):718.
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