NANDA BAGCHI, M.D., Ph.D.; THOMAS R. BROWN, Ph.D.; RONALD F. PARISH, BA., J.D.
To the editor: We read with interest the article by Cooper and colleagues (1) on the usefulness of thyroxine treatment in certain patients with subclinical hypothyroidism. They studied patients who had received treatment for Graves' disease. Another significant group of patients with subclinical hypothyroidism may be found in the elderly population. Significant elevation of serum thyrotrophin with normal serum thyroxine and free thyroxine values have been shown in a large segment of this population (2-4). Elevated serum thyrotrophin levels are one of the most sensitive markers of primary hypothyroidism. Indeed many apparently euthyroid subjects with elevated thyrotrophin levels eventually develop
BAGCHI N, BROWN TR, PARISH RF. Thyroid Function in Older Persons. Ann Intern Med. ;101:718–719. doi: 10.7326/0003-4819-101-5-718_2
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Published: Ann Intern Med. 1984;101(5):718-719.
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