SHOJI SESOKO, M.D.; NAOMICHI MIYAZAKI, M.D.; YOSHIO KATO, M.D.; OSAMU TOCHIKUBO, M.D.; YOSHIHIRO KANEKO, M.D.
To the editor: The relation between parasympathetic nerve activity and hypertension is still not clear, although the mechanisms whereby the sympathetic nervous system affects blood pressure have been clarified in recent studies. To investigate the parasympathetic nerve mechanisms contributing to hypertension, we have been carrying out studies with atropine injections (1, 2) in hypertensive patients. We report a case with evidence that atropine injection induced a hypertensive crisis in a patient with hypertension.
A 28-year-old man was found to have hypertension (blood pressure 188/90 mm Hg) and proteinuria, but not renal dysfunction (serum creatinine level, 1.2 mg/dL) in May 1982.
SESOKO S, MIYAZAKI N, KATO Y, TOCHIKUBO O, KANEKO Y. Atropine and a Hypertensive Crisis. Ann Intern Med. ;101:720. doi: 10.7326/0003-4819-101-5-720_1
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Published: Ann Intern Med. 1984;101(5):720.
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