ROBERT A. HROMAS, M.S., M.D.; J. LEE MURRAY, M.D.
To the editor: The letter by Franco and associates (1) addresses the poorly understood phenomenon of bone marrow depression in the acquired immunodeficiency syndrome. We recently completed a cytologic and cytokinetic analysis of bone marrow from patients with the syndrome that supports and extends the findings by Franco and associates. Bone marrow biopsy samples from eight homosexual men meeting the Center for Disease Control's criteria for the syndrome were obtained, and differential cell counts and flow cytometry were done. Eleven patients were used as controls, ages 35 to 65, with localized solid tumors without histologic evidence of bone marrow involvement.
HROMAS RA, MURRAY JL. Bone Marrow in the Acquired Immunodeficiency Syndrome. Ann Intern Med. ;101:877. doi: 10.7326/0003-4819-101-6-877_1
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Published: Ann Intern Med. 1984;101(6):877.
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