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The number and variety of known antinuclear and anticytoplasmic antibodies that occur in human disease have continued to grow at a pace that threatens to leave the clinician, both specialist and generalist, confused. This succinct and up-to-date monograph defines both the clinical relevance and technical vagaries of tests for antinuclear antibodies.
The first 30 pages provide the most organized and clear synopsis I have seen of the various antinuclear antibodies and their relations to individual connective tissue syndromes. The second chapter describes each of the relevant antigens and the significance of the finding of antibody to each. The principles of
Antinuclear Antibodies: Contemporary Techniques and Clinical Application to Connective Tissue Diseases.. Ann Intern Med. ;101:893. doi: 10.7326/0003-4819-101-6-893_2
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Published: Ann Intern Med. 1984;101(6):893.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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