ALLAN R. RONALD, M.D.; FRANCIS A. PLUMMER, M.D.
Chancroid, one of the six classic venereal diseases, was first described by Brassereau in 1852 (1). He differentiated the "hard" chancre of primary syphilis from the "ulcus molle" of chancroid by showing that autoinoculation with ulcer exudate produced a new ulcer in patients with chancroid but not in patients with primary syphilis. In 1889, Ducrey (2) described a chaining streptobacillary organism in the exudate of ulcers produced by autoinoculation. Subsequent progress in our understanding of this organism has been very slow, because Haemophilus ducreyi is fastidious and chancroid has ceased to be a major health problem in industrialized countries. However,
RONALD AR, PLUMMER FA. Chancroid and Haemophilus ducreyi. Ann Intern Med. ;102:705–707. doi: 10.7326/0003-4819-102-5-705
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Published: Ann Intern Med. 1985;102(5):705-707.
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