RICHARD P. HANDLER, M.D.
To the editor: Perhaps Dr. Steinberg or the other participants in the recent National Institutes of Health conference (1) will comment on any experience they have had with Epstein-Barr virus infection in patients with established rheumatoid arthritis. Because this complication can occur, is it not strong evidence against the etiologic role of Epstein-Barr virus in at least certain cases of rheumatoid arthritis?
One of my patients developed juvenile rheumatoid arthritis at age 8. At age 20 she had an acute febrile illness with profound tonsilitis, fatigue, atypical lymphocytosis, and a positive Monospot test. She recovered fully. Now age 37, she
HANDLER RP. Rheumatoid Arthritis and Epstein-Barr Virus. Ann Intern Med. ;102:865. doi: 10.7326/0003-4819-102-6-865_2
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Published: Ann Intern Med. 1985;102(6):865.
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