VALERIANO FORESTI, M.D.; ELENA PARISIO, M.D.; NADIA SCOLARI, M.D.; LUIGI CARINI, M.D.; C. AUGUSTO LOVAGNINI-SCHER, M.D.
To the editor: Modifications in thyroid function (hypothyroidism and hyperthyroidism) during amiodarone treatment have been reported (1, 2) but how amiodarone could cause the onset of these alterations has not yet been fully explained.
Martino and associates (1) have reported from a retrospective study of 228 patients that hyperthyroidism is more frequent (9.6%) in geographical areas where daily iodine intake is relatively low (West Tuscany, Italy) whereas hypothyroidism appears to be commoner (22%) in areas with normal iodine intake (Worcester, Massachusetts). The authors note that antimicrosomial antibodies (titer of 1:1600 or greater) can be detected with a higher frequency in
FORESTI V, PARISIO E, SCOLARI N, CARINI L, LOVAGNINI-SCHER CA. Amiodarone and Antithyroid Antibodies. Ann Intern Med. ;103:157–158. doi: 10.7326/0003-4819-103-1-157_2
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Published: Ann Intern Med. 1985;103(1):157-158.
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