REED E. PYERITZ, M.D., Ph.D.
Connective tissue pervades all organs and participates in vastly different functions depending, in part, on the type and organization of its biochemical components. The pulmonary system is an instructive example. Over 25% of the dry weight of the lung is connective tissue, including both fibrous elements (collagen and elastin) and ground substance (proteoglycans). Attempts to understand fully the physiologic role of connective tissue in the lung have confronted the theoretic and practical obstacles that have confounded work with other organs. The biochemical components are complex molecules, and their individual characterization is incomplete (1). Moreover, the fibrous and proteoglycan components are
PYERITZ RE. Connective Tissue in the Lung: Lessons from the Marfan Syndrome. Ann Intern Med. ;103:289–290. doi: 10.7326/0003-4819-103-2-289
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Published: Ann Intern Med. 1985;103(2):289-290.
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