PAUL ANDERSON, M.D., Ph.D; JEFFREY MACKLIS, M.D.; MYLES BROWN, M.D.; DANIEL ORY, B.A.
To the editor: Eosinophilic pleocytosis in cerebrospinal fluid is an unusual finding that is often indicative of a parasitic infection of the central nervous system (1). Nonhelminthic causes are rare but have been documented in meningitis due to Coccidioides immitis, Treponema pallidum, and Mycobacterium tuberculosis (1). The rarity of this laboratory finding may narrow the differential diagnosis in cryptic cases of central nervous system disease. We have recently seen a patient with well-documented cryptococcal meningitis who had a marked eosinophilic cerebrospinal fluid pleocytosis that resolved with antifungal therapy.
A 30-year-old woman with a long history of type II diabetes mellitus
ANDERSON P, MACKLIS J, BROWN M, ORY D. Eosinophilic Cerebrospinal Fluid Pleocytosis and Cryptococcal Meningitis. Ann Intern Med. ;103:306–307. doi: 10.7326/0003-4819-103-2-306_2
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Published: Ann Intern Med. 1985;103(2):306-307.
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