MYRON J. TONG, Ph.D., M.D.; RUTH L. CO, R.N.
To the editor: Hepatitis B is endemic in the Asian population and the prevalence of hepatitis B markers is especially high in this group. During adulthood, many persons who are positive carriers of hepatitis B surface antigen (HBsAg) will develop chronic hepatitis, cirrhosis, and primary hepatocellular carcinoma. Perinatal transmission accounts for infection of approximately 50% of the chronic HBsAg-positive carriers, and the remainder are infected during the first few years of life. We provide evidence of additional familial sources for subsequent hepatitis B virus infection to infants who escape perinatal transmission from their HBsAg-positive mothers during birth.
During the course
TONG MJ, CO RL. Hepatitis B Virus Markers in Asian Families. Ann Intern Med. 1985;103:307–308. doi: 10.7326/0003-4819-103-2-307_2
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Published: Ann Intern Med. 1985;103(2):307-308.
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