NEIL E. DOHERTY, M.D.; PETER FUNG, M.D.; MICHELE LEFKOWITZ, M.D.; A. GRAY ELLRODT, M.D.
To the editor: The Annals has shown continued interest in hypothermia (1-3). Most recently, Morris and colleagues (3) have reported that hypothermia does not alter the hemodynamic characteristics of sepsis. Like others (4, 5), they found a significant mortality associated with the concordant presentation of hypothermia and bacteremia. Therefore, we must understand what causes some patients with sepsis to become hypothermic.
We retrospectively studied 26 patients with severe infections, bacteremia, and shock. Patients with core or rectal temperatures below 36.1° C were considered to be hypothermic. A 71% mortality rate was seen among 7 hypothermic patients, compared with a 37%
DOHERTY NE, FUNG P, LEFKOWITZ M, ELLRODT AG. Hypothermia and Sepsis. Ann Intern Med. ;103:308. doi: 10.7326/0003-4819-103-2-308_2
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Published: Ann Intern Med. 1985;103(2):308.
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