WILLIAM P. SHERIDAN, F.R.A.C.P.; GRAEME N. BRODIE, F.R.A.C.P., F.R.C.P.A.
To the editor: Klimo and Connors (1) have achieved impressive results with their chemotherapy for diffuse histiocytic lymphoma in a group of 61 patients, with response rates being equally good in patients with and without adverse prognostic features. However, the only therapy-related death occurred in a patient with extensive gastric invasion by lymphoma, as a result of hemorrhage from an area of tumor necrosis. Thus, one third of the patients with gastrointestinal lymphoma in this study died.
There are data to suggest that surgical resection is feasible in most patients with gastric lymphoma without compromising our ability to deliver effective
WILLIAM P. SHERIDAN, GRAEME N. BRODIE. Treatment of Diffuse Histiocytic Lymphoma. Ann Intern Med. 1985;103:471–472. doi: 10.7326/0003-4819-103-3-471_2
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Published: Ann Intern Med. 1985;103(3):471-472.
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