STEPHEN B. STRUM, M.D.; JONATHAN E. MCDERMED, Pharm.D.
To the editor: In a recent report, Reed and colleagues (1) describe their clinical experience with various subcutaneously implanted catheter systems. In the ten cases described, five had drug extravasation into the skin overlying the access port during overnight infusions. In three cases, resultant tissue injury was severe enough to warrant surgical removal of the vascular access ports.
We agree that the potential for drug extravasation with vascular access ports is real. Our experience with the Port-a-Cath (Pharmacia Hospital Products, Piscataway, New Jersey), however, has shown that the occurrence of drug extravasation with this device is not as common as
STRUM SB, MCDERMED JE. Drug Extravasation and the Port-a-Cath System. Ann Intern Med. 1985;103:472–473. doi: 10.7326/0003-4819-103-3-472_2
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Published: Ann Intern Med. 1985;103(3):472-473.
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