ARNOLD N. COHEN, M.D.
To the editor: Vannatta and colleagues (1) recently reported the case of a patient with recurrent diarrhea caused by Blastocystis hominis. They recommended several drugs for treatment, including emetine, metronidazole, furazolidone, trimethoprim-sulfamethoxazole, iodochlorhydroxyquin, and pentamidine. I report the case of a woman with multiple drug allergies and treatment failures who responded to ketoconazole therapy.
A 76-year-old white woman developed diarrhea in October 1983, after a trip to China and the Mediterranean. Giardia lamblia was found in stool, and she was treated with metronidazole, 750 mg/d for 10 days, with resolution of diarrhea. Within 2 weeks of cessation of treatment, diarrhea
COHEN AN. Ketoconazole and Resistant Blastocystis hominis Infection. Ann Intern Med. ;103:480–481. doi: 10.7326/0003-4819-103-3-480_2
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Published: Ann Intern Med. 1985;103(3):480-481.
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