MICHAEL O. BLACKSTONE, M.D.
To the editor: Wee and Ludwig (1) in their study of liver histology in patients with ulcerative colitis make a distinction between large-duct and small-duct sclerosing cholangitis based on the presence or absence of cholangiographic evidence of sclerosing cholangitis. However, this distinction as it applies to their study hardly seems valid in that cholangiography was done in only 11 of the 37 patients alleged to have small-duct disease, and in at least 6 of these 11 it appears to have been intravenous cholangiography, a notoriously inaccurate means of studying the biliary system (2). Indeed, these 6 patients were later found
BLACKSTONE MO. Sclerosing Cholangitis. Ann Intern Med. ;103:635. doi: 10.7326/0003-4819-103-4-635_1
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Published: Ann Intern Med. 1985;103(4):635.
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