MARK A. KANE, M.D.; STEPHEN C. HADLER, M.D.; JAMES E. MAYNARD, M.D., PH.D.
The availability of a safe and effective hepatitis B vaccine has stimulated debate about the most effective ways to use this product. Because the vaccine is costly and because tests for hepatitis B antibody are widely available, physicians have the option of using one or more antibody tests to screen for susceptibility before administering the vaccine. Most persons with hepatitis B virus infection develop antibodies to both the hepatitis B surface antigen (anti-HBs) and core antigen (anti-HBc); therefore, a test for either antibody can detect persons who are immune. Nevertheless, recent reports have introduced doubt about the reliability of screening
KANE MA, HADLER SC, MAYNARD JE. Antibody to Hepatitis B Surface Antigen and Screening Before Hepatitis B Vaccination. Ann Intern Med. ;103:791–793. doi: 10.7326/0003-4819-103-5-791
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Published: Ann Intern Med. 1985;103(5):791-793.
Gastroenterology/Hepatology, Infectious Disease, Vaccines/Immunization, Viral Hepatitis.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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