LEONARD H. SIGAL, M.D.
To the editor: Only 2 years ago, the causative agent of Lyme disease was isolated (1) and now a diagnostic serologic test is available (2) to document the expanding geographic and clinical range of the disease. In their editorial, Duffy and Mertz (2) point out that coexisting babesia and borrelia infections make the question of the true etiopathogenesis unclear in the patient of Marcus and colleagues (3). Certainly, positive serologic tests document a previous encounter with B. burgdorferi, but they do not assure that current maladies are due to Lyme disease.
We have tested mononuclear cells from patients with Lyme
LEONARD H. SIGAL. Response of Mononuclear Cells to Borrelia burgdorferi. Ann Intern Med. 1985;103:808–809. doi: 10.7326/0003-4819-103-5-808_3
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Published: Ann Intern Med. 1985;103(5):808-809.
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