STUART M. LICHTMAN, M.D.; PHILIP SCHULMAN, M.D.
To the editor: A recent editorial (1) has discussed the complexities of the myelodysplastic syndromes. Although the cause of most cases is unknown, the occurrence of myelodysplastic syndromes after treatment of a primary malignancy with chemotherapy has been increasingly recognized (1). These syndromes are commoner after treatment of hematologic disorders, but their occurrence after solid tumors is also occurring in greater frequency. Recently, Boice and colleagues (2) have reported the leukemogenic effect of semustine (methyl-CCNU). We now report a case of carmustine (BCNU)-induced myelodysplasia.
A 64-year-old white man had evaluation of the right eye for ocular melanoma in March 1982,
LICHTMAN SM, SCHULMAN P. Carmustine and Myelodysplasia. Ann Intern Med. 1985;103:964–965. doi: 10.7326/0003-4819-103-6-964_3
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Published: Ann Intern Med. 1985;103(6_Part_1):964-965.
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