GEORGE A. BRAY, M.D.
The major diseases associated with obesity are hypertension, atherosclerosis, and diabetes, as well as certain types of cancer. Less well-known complications include hepatic steatosis, gallbladder disease, pulmonary function impairment, endocrine abnormalities, obstetric complications, trauma to the weight-bearing joints, gout, cutaneous disease, proteinuria, increased hemoglobin concentration, and possibly immunologic impairment. A U- or J-shaped curve illustrates the relation between body mass index and the degree of these various complications. This relationship can be used to provide guidelines for assessing treatment of obesity.
BRAY GA. Complications of Obesity. Ann Intern Med. 1985;103:1052–1062. doi: 10.7326/0003-4819-103-6-1052
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Published: Ann Intern Med. 1985;103(6_Part_2):1052-1062.
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