VITTORIO E. ANDREUCCI, M.D.; GIUSEPPE CONTE, M.D.; ANTONIO DAL CANTON, M.D.
To the editor: In his report on captopril-induced renal insufficiency (1), Dr. Hricik confirms our results published in 1984 (2) and presented in June 1984 at the Congress of the International Society of Nephrology in Los Angeles.
In our opinion, however, the impairment of renal function after administration of 25 mg of captopril during sodium depletion is not due to captopril, but to the combination of a fall in blood pressure and sodium depletion; unfortunately neither renal function nor blood pressure were evaluated immediately before administration of captopril. The decrease in blood pressure was probably not due to captopril (the
ANDREUCCI VE, CONTE G, CANTON AD. Captopril and Impaired Renal Function. Ann Intern Med. 1986;104:283. doi: 10.7326/0003-4819-104-2-283_1
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Published: Ann Intern Med. 1986;104(2):283.
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