DAVID M. FERNEY, M.D.; KATHERINE DESCHRYVER-KECSKEMETI, M.D.; RAY E. CLOUSE, M.D.
To the editor: The Cronkhite-Canada syndrome is characterized by nonfamilial, generalized, gastrointestinal polyposis (retention type) associated with diarrhea, weight loss, and ectodermal changes (1). The attendant effects of the disorder on nutrient absorption and food intake with concomitant intestinal protein losses can result in inanition. Remissions of this idiopathic syndrome have been reported, yet the prognosis is generally considered poor; many deaths are attributable to malnutrition (2, 3). We recently evaluated a patient with classic features of the syndrome.
A 66-year-old white man had had 6 months of progressive anorexia, hypogeusia, vomiting, and diarrhea accompanied by complete loss of scalp
FERNEY DM, DESCHRYVER-KECSKEMETI K, CLOUSE RE. Treatment of Cronkhite-Canada Syndrome with Home Total Parenteral Nutrition. Ann Intern Med. ;104:588. doi: 10.7326/0003-4819-104-4-588_2
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Published: Ann Intern Med. 1986;104(4):588.
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