B. CLOTET, M.D.; M. GRIFOL, M.D.; J. BOIX, M.D.; J. JUNCA, M.D.; M. FOZ, M.D.; M. RIBAS, M.D.
To the editor: A recent article by Tavitian and colleagues (1) concerns the diagnosis and treatment of esophageal candidiasis in patients with the acquired immunodeficiency syndrome (AIDS). The authors initiate therapy if the patient has oral thrush and symptoms of esophageal disease. Endoscopy is reserved for confirmation of esophageal candidiasis in patients who continue to have symptoms despite antifungal therapy.
Esophageal candidiasis may be asymptomatic and not associated with oral thrush. We have examined, at admission, 24 patients with AIDS-related complex using endoscopy as a staging procedure for a research protocol. No patient had oral candidiasis or symptoms of esophageal disease. In 4 patients (17%), esophagoscopy showed dense plaques of white exudate. Cytologic examination of esophageal
CLOTET B, GRIFOL M, BOIX J, JUNCA J, FOZ M, RIBAS M. Complications of the Acquired Immunodeficiency Syndrome. Ann Intern Med. 1986;104:726–727. doi: 10.7326/0003-4819-104-5-726
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Published: Ann Intern Med. 1986;104(5):726-727.
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