M. CASTRO GARCÍA, M.D.; M. POSADA, M.D.; F. DIAZ DE ROJAS, M.D.; I. ABAITUA BORDA, M.D.; J. M. TABUENCA OLIVER, M.D.
To the editor: In his exhaustive review of the hypercoagulable states (1), Schafer makes no mention of the situation caused by those diseases having increased eosinophil counts, the most evident of which might be the hypereosinophilic syndrome. Regarding this entity, there have been reports of arterial intimal lesions, which might explain the trend to thromboembolic phenomena (2), but there also are procoagulating substances released by both the macrophages (3) and eosinophils (2) in these patients.
We in Spain have had the opportunity to observe a new clinical entity, the toxic oil syndrome (4), with its symptoms of eosinophilia, endothelial damage,
GARCÍA MC, POSADA M, DIAZ DE ROJAS F, BORDA IA, OLIVER JMT. Hypercoagulable States and the Toxic Oil Syndrome. Ann Intern Med. ;104:730. doi: 10.7326/0003-4819-104-5-730_1
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Published: Ann Intern Med. 1986;104(5):730.
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