CONSTANCE A. BENSON, M.D.; HAROLD A. KESSLER, M.D.; ALAN A. HARRIS, M.D.; KATHI KAPELL, M.S.; SANDRA CHAKONAS, M.S., M.T.
To the editor: Both the need for prevaccination screening for hepatitis B virus infection among health care workers and the most appropriate and cost-effective test for screening remain undecided. Kessler and colleagues (1) recommend testing for antibody to hepatitis B core antigen (anti-HBc) as a prevaccination screen. Their data suggest that currently available assays for antibody to hepatitis B surface antigen (anti-HBs) are inadequate when used as the sole test to detect all persons susceptible to hepatitis B virus infection. However, Werner and coworkers (2) suggest the most practical screening test is that for anti-HBs, but they propose a cutoff
BENSON CA, KESSLER HA, HARRIS AA, KAPELL K, CHAKONAS S. Enzyme Immunoassay Screening for Hepatitis B Immunization. Ann Intern Med. ;104:730–731. doi: 10.7326/0003-4819-104-5-730_2
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Published: Ann Intern Med. 1986;104(5):730-731.
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