MARK L. GRABER, M.D.; GERALD SCHULMAN, M.D.
Hypocalcemia, common in patients with magnesium depletion, has been attributed to either defective release of parathyroid hormone, resistance to the hormone's peripheral effects, or a combination of the two (1). We report a case that suggests that this hypocalcemia may simply represent a direct effect of magnesium depletion on bone independent of the effects of parathyroid hormone. A 68-year-old man presented with a thyroid mass. A biopsy specimen showed recurrence of a squamous cell carcinoma of a vocal cord that had been removed 4 years previously. His nutritional status was normal, as were all electrolyte determinations, including plasma concentrations of
GRABER ML, SCHULMAN G. Hypomagnesemic Hypocalcemia Independent of Parathyroid Hormone. Ann Intern Med. ;104:804–805. doi: 10.7326/0003-4819-104-6-804
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Published: Ann Intern Med. 1986;104(6):804-805.
Endocrine and Metabolism, Fluid and Electrolyte Disorders, Nephrology.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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